The Margherita pizza is widely regarded as the most famous pizza globally. Originating from Naples, Italy, it features a simple yet flavorful combination of ingredients: fresh tomatoes, mozzarella cheese, basil, salt, and olive oil. This classic pizza is not only a staple in Italian cuisine but also a favorite worldwide.

One of the most renowned establishments serving traditional Neapolitan pizza is Antica Pizzeria Port'Alba in Naples. Established in 1830, it is often cited as the world's first pizzeria. Initially starting as a stand for peddlers in 1738, it transitioned into a full-fledged pizzeria, becoming a popular meeting place for artists, students, and locals. The pizzeria continues to operate today, maintaining its historic charm and culinary traditions.

In recent years, Una Pizza Napoletana in Manhattan, New York, has gained international acclaim. In 2024, it was honored as the best pizzeria in the world by 50 Top Pizza, surpassing renowned Italian establishments. Owner Anthony Mangieri is celebrated for his dedication to traditional pizza-making techniques, focusing on classic varieties like the Marinara, Margherita, and Cosacca pizzas.

These establishments exemplify the enduring appeal and cultural significance of pizza, each contributing uniquely to its rich history and global popularity.